Testosterone Gel

Testosterone gel is a topical medication used for testosterone replacement therapy (TRT). It is a hydroalcoholic gel or solution that is applied to the skin, where it is absorbed and slowly releases testosterone into the bloodstream. This method provides a more consistent level of testosterone in the body compared to injections, which can cause peaks and troughs in hormone levels.

Testosterone gel is prescribed to adult males with conditions related to low or absent testosterone levels, a condition known as hypogonadism. Symptoms of hypogonadism can include:

• Low sex drive

• Erectile dysfunction

• Fatigue and decreased energy

• Loss of muscle and bone mass

• Depressed mood

• Infertility

The gel is a transdermal delivery system. When applied to clean, dry skin, the alcohol in the gel evaporates, allowing the testosterone to be absorbed through the skin. The skin acts as a reservoir, providing a sustained and steady release of the hormone over a 24-hour period. This helps to restore testosterone levels to a normal range.

The gel is for external use only and is typically applied once a day in the morning. It should be applied to specific areas of the body, such as the shoulders, upper arms, or abdomen, depending on the specific brand. It is important to follow the product's instructions carefully.

• Application: The gel should be spread as a thin layer and allowed to dry for several minutes before dressing.

• Hygiene: It is crucial to wash your hands with soap and water immediately after application to prevent accidental transfer of the medication to other people.

• Secondary Exposure Risk: A key precaution with testosterone gel is the risk of transferring the medication to women or children through skin-to-skin contact. This can cause serious side effects in women (e.g., changes in body hair and voice) and children (e.g., early puberty, enlarged genitals). The treated area should be covered with clothing once the gel is dry.

Common side effects of testosterone gel include:

• Skin Reactions: Redness, itching, burning, or irritation at the application site.

• Acne

• Increased red blood cell count: This can thicken the blood and increase the risk of blood clots, heart attack, or stroke.

• Fluid retention: Swelling in the ankles, feet, or hands.

• Increased PSA levels: Prostate-specific antigen (PSA) levels may increase, which requires monitoring as it can be a marker for prostate issues.

• Breast enlargement or tenderness (gynecomastia)

• Mood changes: Including mood swings and irritability.