Abiraterone 250 Mg Tablets

Abiraterone 250mg tablets are a medication used to treat prostate cancer that has spread to other parts of the body. Here\\\'s a detailed description:

What it is:

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  Active Ingredient: Abiraterone acetate (each 250mg tablet contains 250 mg abiraterone acetate, equivalent to 223 mg of abiraterone).

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  Class of Medication: Androgen biosynthesis inhibitor. It works by decreasing the amount of certain hormones (androgens like testosterone) in the body, which can slow the growth of prostate cancer.

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  Form: Oral tablet, typically film-coated.

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Uses:

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  It is used in combination with prednisone or prednisolone to treat:

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    Metastatic castration-resistant prostate cancer (mCRPC): Prostate cancer that has spread and is no longer responding to treatments that lower testosterone levels (surgical or medical castration).

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    Metastatic high-risk castration-sensitive prostate cancer (mCSPC): Prostate cancer that has spread but is still responding to hormone therapy, specifically when it\\\'s considered high-risk.

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Dosage and Administration:

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  The typical recommended dose is 1,000 mg (four 250 mg tablets) as a single daily dose.

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  Important: Abiraterone must be taken on an empty stomach. This means taking it at least 1 hour before or 2 hours after eating any food. Taking it with food significantly increases the absorption of abiraterone, which can lead to increased side effects.

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  It is usually taken once daily at around the same time each day.

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  It is crucial to take abiraterone exactly as directed by your doctor and not to break, crush, or chew the tablets.

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  Prednisone or prednisolone is prescribed alongside abiraterone to help manage potential side effects related to increased mineralocorticoid levels (e.g., high blood pressure, fluid retention, low potassium).

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Side Effects: Abiraterone can cause various side effects, some common and some serious. It\\\'s important to monitor for these and report them to your doctor.

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  Common Side Effects (may affect more than 1 in 10 people):

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    Fluid retention (swelling in legs or feet)

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    Low blood potassium (hypokalemia)

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    Increased liver function test results

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    High blood pressure (hypertension)

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    Urinary tract infection

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    Diarrhea

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    Joint swelling/discomfort

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    Muscle discomfort

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    Cough

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    Upper respiratory tract infection

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    Insomnia

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    Constipation

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    Dyspepsia (indigestion)

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