Rabeprazole Domperidone Capsule

Rabeprazole and Domperidone is a combination medication that is widely used to treat various gastrointestinal conditions. It is not a single branded product but a combination of two active pharmaceutical ingredients (APIs), often sold under various brand names.

• Rabeprazole: This is a Proton Pump Inhibitor (PPI). It works by blocking a specific enzyme in the stomach lining called the "proton pump" or H+/K+ ATPase, which is the final step in the production of stomach acid. By inhibiting this pump, rabeprazole significantly reduces the amount of acid the stomach produces.

   
   

   

• Domperidone: This is a prokinetic and anti-emetic (anti-nausea) agent. It works by increasing the movement of the stomach and intestines. This action helps to accelerate gastric emptying (the speed at which food leaves the stomach), which reduces the feeling of fullness, bloating, and prevents the backflow of stomach contents into the esophagus.

   
   
   

   

This combination capsule is prescribed to address conditions where both acid suppression and improved gastrointestinal motility are necessary. Its primary uses include:

• Gastroesophageal Reflux Disease (GERD): Also known as acid reflux, this condition is characterized by a backflow of stomach acid into the esophagus. The combination of rabeprazole to reduce acid and domperidone to prevent backflow is highly effective in treating GERD and its symptoms, such as heartburn, belching, and indigestion.

   
   

   

• Peptic Ulcer Disease: By reducing stomach acid, the medication helps to heal ulcers in the stomach and duodenum (the first part of the small intestine).

   

   

• Dyspepsia: It provides relief from symptoms of indigestion, including bloating, nausea, and discomfort in the upper abdomen.

   

   

The capsule is typically taken orally, usually once daily, on an empty stomach, about 30 to 60 minutes before the first meal of the day. It is important to swallow the capsule whole and not crush, chew, or break it, as this can interfere with its extended-release properties. The exact dosage and duration of treatment should be determined by a healthcare professional.

Common side effects of this combination medication are generally mild and may include:

• Headache

   

   

• Diarrhea or constipation

   

   

• Nausea

   

   

• Abdominal pain or flatulence

   

   

• Dry mouth

   

   

• Dizziness