Tenofovir Alafenamide (TAF) is an antiviral medication that is a prodrug of tenofovir. It is used to treat chronic hepatitis B virus (HBV) infection and is also a key component in combination therapies for the treatment and prevention of HIV-1 infection. TAF is a newer formulation of tenofovir that is designed to be more effective at lower doses and have a better safety profile, particularly regarding kidney and bone health, compared to its predecessor, tenofovir disoproxil fumarate (TDF).

Tenofovir Alafenamide is indicated for:

• Chronic Hepatitis B Virus (HBV) Infection: It is used in adults and children who have compensated liver disease.

• HIV-1 Infection: TAF is not used alone for HIV, but is a crucial part of combination single-tablet regimens (STRs) for treating and preventing HIV-1 in adults and adolescents. These combination products may include other antiretrovirals like emtricitabine, bictegravir, and cobicistat.

Tenofovir Alafenamide is a nucleotide reverse transcriptase inhibitor (NRTI). Once it's absorbed by the body, TAF is converted into tenofovir. This active form then interferes with the reverse transcriptase enzyme used by both the HBV and HIV viruses to replicate their genetic material. By blocking this process, the medication helps to reduce the amount of virus in the body, which can help to control the disease and prevent further damage to organs like the liver.

Tenofovir Alafenamide is taken orally as a tablet, typically once a day with food. It is crucial to follow the prescribed dosage and not to miss any doses, as this can lead to the virus developing resistance to the medication, making it ineffective.

While TAF is considered to have a better safety profile than TDF, it can still cause side effects. Common side effects may include:

• Headache

• Nausea and vomiting

• Diarrhea

• Abdominal pain

• Fatigue

• Cough

• Back and joint pain

Serious side effects are less common but can occur. You should contact your doctor immediately if you experience:

• Severe Acute Exacerbation of Hepatitis B: If you have HBV and stop taking the medication, your hepatitis B could worsen, potentially leading to liver failure.

• Lactic Acidosis: A buildup of lactic acid in the blood, which can be a serious medical emergency. Symptoms include unusual muscle pain, difficulty breathing, and stomach pain with nausea and vomiting.

• Liver Damage: Symptoms can include yellowing of the skin or eyes (jaundice), dark urine, and stomach pain.

• Kidney Problems: Though less common than with TDF, TAF can still cause kidney damage. Your doctor will monitor your kidney function regularly.

Tenofovir Disoproxil Fumarate (TDF) is a prescription antiviral medication. It is a prodrug, meaning it is converted into its active form, tenofovir, inside the body. TDF belongs to a class of drugs called nucleotide reverse transcriptase inhibitors (NtRTIs).

Tenofovir works by inhibiting a crucial viral enzyme called reverse transcriptase. This enzyme is essential for the viruses to replicate and multiply. By blocking this enzyme, tenofovir prevents the viruses from creating new copies of themselves, thereby controlling the infection and reducing the viral load in the body.

Tenofovir disoproxil fumarate is approved for the treatment of:

• HIV-1 Infection: It is used in combination with other antiretroviral medications as part of a highly active antiretroviral therapy (HAART) regimen to manage HIV infection in adults and children. It helps to reduce the amount of HIV in the blood and can help prevent or reverse damage to the immune system.

   
   

   

• Chronic Hepatitis B (HBV) Infection: It is also used to treat chronic hepatitis B, as it is effective against the virus and can help reduce liver damage.

   

   

It is important to note that tenofovir is not a cure for HIV or hepatitis B. It helps to manage the conditions but does not eliminate the viruses from the body.

Tenofovir Disoproxil Fumarate is available in various tablet strengths, including 150 mg, 200 mg, 250 mg, and 300 mg. The standard dose is typically 300 mg once a day. The tablet can be taken with or without food, though taking it with a meal may help if it causes stomach upset. It is crucial to take the medication exactly as prescribed and not to skip doses, as this can lead to the virus developing resistance to the drug.

Common side effects of TDF are often mild and may include:

• Nausea and vomiting

   

   

• Diarrhea

   

   

• Headache

   

   

• Dizziness

   

   

• Weakness or fatigue

   

   

• Rash

   

   

While generally well-tolerated, TDF can cause serious side effects, and patients should be monitored regularly by their healthcare provider.

• Kidney Problems: TDF can cause kidney damage, so patients with pre-existing kidney disease or other risk factors need to be monitored closely. Regular blood tests are necessary to check kidney function.

Tofajak Tablets contain the active ingredient Tofacitinib. It is a prescription medication that belongs to a class of drugs called Janus kinase (JAK) inhibitors.

Tofacitinib works by targeting and blocking the Janus kinase (JAK) enzymes. These enzymes are part of a critical signaling pathway that regulates the production of inflammatory cytokines. Cytokines are small proteins that act as messengers in the immune system, and an overproduction of them can lead to the inflammation that characterizes autoimmune and inflammatory diseases. By inhibiting the JAK enzymes, Tofacitinib reduces the activity of the immune system and lowers inflammation.

Tofajak Tablets are used to treat several chronic inflammatory and autoimmune conditions, particularly in patients who have not responded well to other treatments. The main uses include:

• Rheumatoid Arthritis: It is used to treat moderate to severe active rheumatoid arthritis in adults. It helps reduce joint pain, stiffness, and swelling and can slow down the progression of joint damage.

• Psoriatic Arthritis: It is used to treat active psoriatic arthritis, a condition that affects some people with psoriasis, causing joint pain, stiffness, and swelling.

• Ankylosing Spondylitis: It is used to treat this rare form of arthritis that primarily affects the spine.

• Ulcerative Colitis: It is used to treat moderate to severe active ulcerative colitis, an inflammatory bowel disease that affects the large intestine.

• Juvenile Idiopathic Arthritis: It can also be used to treat active polyarticular juvenile idiopathic arthritis in children.

• Tofajak is taken orally, usually as a tablet.

• The dosage and frequency (e.g., once or twice daily) are determined by the doctor based on the specific condition being treated and the patient's response.

• It can be taken with or without food.

• It is important to take the medication exactly as prescribed and not to stop taking it abruptly without consulting a doctor.

Because Tofacitinib affects the immune system, it can increase the risk of certain side effects.

Common Side Effects:

• Upper respiratory tract infections (like the common cold)

• Headache

• Diarrhea

• Nausea

• Increased cholesterol levels

Serious Side Effects:

• Serious Infections: Tofacitinib can make a person more susceptible to serious infections, including tuberculosis (TB) and shingles. Patients should be tested for TB before starting treatment.

• Blood Clots: There is an increased risk of blood clots in the legs (deep vein thrombosis) or lungs (pulmonary embolism), especially in patients with certain risk factors.

• Cardiovascular Events: In some studies, a higher dose of Tofacitinib has been associated with an increased risk of major cardiovascular events like heart attack and stroke, particularly in patients who are 50 years of age or older with at least one heart disease risk factor.

• Cancers: The drug may increase the risk of certain cancers, particularly lymphoma.

• Changes in Blood Counts: It can cause a decrease in blood cell counts, including a low white blood cell count (neutropenia) and low red blood cell count (anemia). Regular blood tests are necessary to monitor this.

• Prescription-only: Tofajak is a powerful medication and requires a doctor's prescription and close medical supervision.

• Pregnancy and Breastfeeding: It is not recommended for use during pregnancy, as it can be harmful to a fetus. Women of child-bearing potential must use effective contraception during and for a period after treatment. It is also not recommended while breastfeeding.

• Vaccinations: Patients should consult their doctor before getting any vaccines, especially live vaccines, as the drug can affect the immune response.

Trustiva Tablets are a fixed-dose combination of three antiviral medicines used for the treatment of Human Immunodeficiency Virus (HIV) type 1 infection. This medication is a part of combination antiretroviral therapy (ART) and works by helping to control the virus, reduce the viral load, and improve immune function.

Trustiva tablets contain a combination of three active ingredients:

• Efavirenz (600 mg): A non-nucleoside reverse transcriptase inhibitor (NNRTI).

   
   

   

• Emtricitabine (200 mg): A nucleoside reverse transcriptase inhibitor (NRTI).

   

   

• Tenofovir Disoproxil Fumarate (300 mg): A nucleotide reverse transcriptase inhibitor (NtRTI).

   
   

   

These drugs work together to block a critical enzyme called reverse transcriptase, which the HIV virus needs to replicate. By stopping this process, Trustiva helps to reduce the amount of virus in the body and strengthens the immune system to fight off infections.

• Treatment of HIV-1 infection: Trustiva is used as a complete regimen or in combination with other antiretroviral agents for adults and adolescents with HIV-1 infection.

   

   

• Viral Suppression: It helps to reduce the viral load, which is the amount of HIV in the blood, and prevent the progression of HIV to AIDS.

   

   

• The typical dosage for adults and adolescents weighing at least 40 kg is one tablet once a day.

   

   

• It is generally recommended to take Trustiva on an empty stomach, preferably at bedtime. Taking it at bedtime can help to reduce common side effects like dizziness and trouble sleeping.

   
   

   

• It is crucial to take the medication regularly and not skip doses to prevent the virus from developing drug resistance.

   

   

While Trustiva is effective, it can cause various side effects. These may include:

• Dizziness, drowsiness, and fatigue

   

   

• Gastrointestinal issues such as nausea, vomiting, and diarrhea

   

   

• Headache

   

   

• Skin rash

   

   

• Abnormal dreams or nightmares

   

   

• Mental Health: This medication can cause serious psychiatric side effects, including severe depression, anxiety, hallucinations, and suicidal thoughts. Patients with a history of mental illness should be closely monitored.

   

   

• Kidney and Liver Health: Trustiva can affect kidney and liver function. Regular monitoring of these organs with blood tests may be necessary.

   
   

   

• Bone Density: Long-term use of Tenofovir can lead to a decrease in bone mineral density. Your doctor may recommend calcium and vitamin D supplements.

   
   

   

• Pregnancy: Trustiva may cause birth defects. It is critical for women of childbearing potential to use effective contraception during treatment and for 12 weeks after stopping the medication.

   

   

• Drug Interactions: Trustiva can interact with other medications, including certain antifungals, anticonvulsants, and herbal supplements like St. John's wort. Always inform your doctor about all the medicines you are taking

Valacyclovir tablets, commonly known by the brand name Valtrex, are an antiviral medication used to treat infections caused by the herpes virus. It is a prodrug, meaning that once it is absorbed by the body, it is converted into the active antiviral drug, acyclovir.

Valacyclovir works by inhibiting viral DNA synthesis. The drug, once converted to acyclovir, competes with natural building blocks of DNA for incorporation into the virus's genetic material. This process effectively halts the replication of the virus, slowing its growth and spread within the body.

Valacyclovir is prescribed to treat a variety of herpes infections, including:

• Herpes Zoster (Shingles): Used to treat the painful rash caused by the varicella-zoster virus.

• Genital Herpes: Used for treating initial and recurrent outbreaks and for long-term suppressive therapy to reduce the frequency of future outbreaks. It can also reduce the risk of transmission to a sexual partner.

• Herpes Labialis (Cold Sores): Used to treat cold sores on the mouth and face.

• Chickenpox: Prescribed to treat chickenpox in children.

It's important to note that while valacyclovir can help manage symptoms, it does not cure the herpes infection. The virus remains dormant in the body between outbreaks.

The dosage and duration of treatment vary depending on the specific condition being treated, the patient's age, and their kidney function. It's crucial to follow the doctor's instructions exactly and complete the full course of treatment, even if symptoms improve. Common dosages include:

• Shingles: 1 gram three times a day for 7 days.

• Genital Herpes (initial outbreak): 1 gram twice a day for 10 days.

• Genital Herpes (recurrent outbreak): 500 mg twice a day for 3 days.

• Cold Sores: 2 grams twice a day for 1 day, taken 12 hours apart.

Valacyclovir can be taken with or without food.

Common side effects of valacyclovir include:

• Headache

• Nausea

• Stomach pain

• Diarrhea

In some cases, more serious side effects can occur, and you should seek immediate medical attention if you experience:

• Signs of a severe allergic reaction (hives, difficulty breathing, swelling of the face or throat)

• Confusion, hallucinations, or agitation

• Signs of kidney injury (decreased urine output, swelling in the hands or feet)

Super Vilitra is a combination medication that contains two active ingredients: vardenafil and dapoxetine. It is used to treat two common male sexual dysfunctions: erectile dysfunction (ED) and premature ejaculation (PE). This medication is not approved by the FDA in the United States, but it is available in other countries.

• Vardenafil (20mg): This is a phosphodiesterase type 5 (PDE5) inhibitor. It works similarly to other ED medications like sildenafil (Viagra). During sexual stimulation, vardenafil helps relax the blood vessels in the penis, increasing blood flow to enable an erection.

• Dapoxetine (60mg): This is a selective serotonin reuptake inhibitor (SSRI) that is specifically formulated for "on-demand" use. It helps to increase the level of serotonin in the nervous system, which in turn improves control over ejaculation and increases the time taken to ejaculate.

Super Vilitra is used to address the dual issues of:

• Erectile Dysfunction (ED): The inability to get or maintain an erection firm enough for sexual activity.

• Premature Ejaculation (PE): Ejaculating sooner than a man or his partner would like.

The typical dosage is one tablet containing 20mg of vardenafil and 60mg of dapoxetine. It is usually taken orally with a glass of water approximately 1 to 3 hours before sexual activity. It should not be taken more than once in a 24-hour period.

Because Super Vilitra combines two different drugs, the side effects can be a combination of those from both vardenafil and dapoxetine. Common side effects may include:

• From Vardenafil: Headache, flushing, stuffy or runny nose, dizziness, and indigestion.

• From Dapoxetine: Nausea, dizziness, dry mouth, and fatigue.

More serious side effects can occur, and if you experience any of the following, you should seek immediate medical attention:

• A prolonged and painful erection (priapism) lasting more than 4 hours.

• Sudden loss of vision or hearing.

• Chest pain, shortness of breath, or an irregular heartbeat.

• Signs of an allergic reaction, such as a rash, hives, or swelling of the face, lips, or tongue.

• Nitrates: Do not take Super Vilitra if you are on any medication containing nitrates for chest pain or heart problems. The combination can cause a life-threatening drop in blood pressure.

• Cardiovascular Health: Men with pre-existing heart conditions, a history of heart attack or stroke, or low blood pressure should consult a doctor before using this medication.

• Kidney or Liver Issues: Dosage adjustments may be necessary for individuals with impaired kidney or liver function.

• Other Medications: Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements, as they can interact with the components of Super Vilitra.

• Alcohol: Avoid or limit alcohol consumption while taking this medication, as it can increase the risk of side effects like dizziness.

Vardenafil is a medication used to treat erectile dysfunction (ED) in men. The 20mg dose is typically the maximum strength available and is prescribed when lower doses have been found to be ineffective. Vardenafil belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors, which also includes sildenafil (Viagra) and tadalafil (Cialis).

Like other PDE5 inhibitors, vardenafil works by increasing blood flow to the penis during sexual stimulation. In a sexually aroused state, the body releases nitric oxide, which leads to the production of a chemical called cyclic guanosine monophosphate (cGMP). cGMP causes the smooth muscles in the blood vessels of the penis to relax, allowing for increased blood flow and resulting in an erection. The PDE5 enzyme normally breaks down cGMP. By inhibiting this enzyme, vardenafil allows cGMP to accumulate, maintaining the increased blood flow and enabling an erection to be achieved and sustained. It is crucial to understand that sexual stimulation is necessary for the medication to work.

Vardenafil 20mg tablets are primarily used for the treatment of erectile dysfunction. It is a potent dose, and studies have shown it to be particularly effective in difficult-to-treat cases, such as in men with diabetes-associated ED.

• Standard Dose: The typical starting dose for vardenafil is 10mg. A doctor may increase the dose to 20mg if the lower dose is not providing the desired effect.

   

   

• Maximum Dose: 20mg is the maximum recommended dose. It should not be taken more than once per day.

   
   

   

• Timing: Vardenafil tablets are usually taken about 60 minutes before sexual activity. It can be taken with or without food, though a high-fat meal may delay its onset of action.

   
   

   

Common side effects of vardenafil include:

• Headache

   

   

• Flushing (redness of the face)

   

   

• Stuffy or runny nose

   

   

• Dizziness

   

   

• Upset stomach or indigestion

   

   

More serious, but less common, side effects require immediate medical attention:

• Priapism: A prolonged and painful erection lasting more than four hours. If left untreated, this can cause permanent damage to the penis.

   
   

   

• Sudden Vision or Hearing Loss: A rare but serious side effect that requires immediate medical care.

   

   

• Cardiovascular Symptoms: Chest pain, irregular heartbeat, or a sudden drop in blood pressure.

Velpanat is a brand name for a fixed-dose combination of two antiviral medications: Sofosbuvir and Velpatasvir. It is used to treat chronic hepatitis C virus (HCV) infection.

The two active ingredients in Velpanat work together to inhibit the replication of the hepatitis C virus:

• Sofosbuvir (400 mg): This is a nucleotide analog polymerase inhibitor. It targets and blocks the NS5B polymerase enzyme, which the hepatitis C virus needs to copy its genetic material (RNA). By inhibiting this enzyme, Sofosbuvir stops the virus from multiplying.

   
   

   

• Velpatasvir (100 mg): This is an NS5A inhibitor. It targets and blocks the NS5A protein, which is another crucial component for the virus to assemble new particles and replicate.

   

   

The combination of these two drugs offers a highly effective, pan-genotypic (effective against all six main genotypes of HCV) treatment. It has very high cure rates, often over 90%, for a wide range of patients.

Velpanat is primarily used for the treatment of:

• Chronic Hepatitis C Virus (HCV) Infection: It is indicated for adults and adolescents with chronic HCV infection, with or without cirrhosis (scarring of the liver). In some cases, it may be used with another antiviral medication, ribavirin, especially in patients with more advanced liver disease.

   
   

   

The drug works by lowering the viral load (the amount of virus in the blood) and eventually clearing the virus from the body, which helps to prevent long-term liver damage, such as cirrhosis, liver failure, and liver cancer.

• Velpanat is taken orally as a tablet, typically once a day.

   

   

• It can be taken with or without food.

   

   

• The usual treatment duration is 12 weeks, but a doctor will determine the exact duration and dosage based on the patient's specific condition.

   

   

• It is crucial to take the medication as prescribed and to complete the entire course of treatment, even if symptoms improve, to ensure the virus is completely eradicated and to prevent the development of drug-resistant strains.

   

   

Velpanat is generally well-tolerated, and side effects are often mild. The most common side effects include:

• Headache

   

   

• Fatigue or tiredness

   

   

• Nausea and vomiting

   

   

• Diarrhea

   

   

• Insomnia (difficulty sleeping)

   

   

More serious, but less common, side effects can occur. Patients should seek immediate medical attention if they experience:

• A life-threateningly slow heart rate (bradycardia), especially if they are also taking amiodarone (a heart medication).

   

   

• Signs of liver problems, such as yellowing of the skin or eyes (jaundice).

   

   

• Prescription-only: Velpanat is a powerful medication and must be used under the close supervision of a healthcare professional, typically a specialist in liver disease or infectious diseases.

   

   

• Drug Interactions: Velpanat has significant interactions with several other medications, including proton pump inhibitors (PPIs), antacids, and certain heart medications like amiodarone. It is essential to inform the doctor about all other medications, supplements, and herbal products being taken.

   

   

• Hepatitis B Reactivation: Before starting treatment, all patients should be screened for hepatitis B virus (HBV) infection. In some cases, HCV treatment can lead to a reactivation of a previously inactive HBV infection, which can cause serious liver complications.

Please be aware that "Veltasof" and "Veltas" are different medications with different active ingredients and uses. The information provided here is for Veltasof Tablets, which are used to treat hepatitis C.

Veltasof Tablets are a fixed-dose combination of two antiviral medicines used for the treatment of chronic hepatitis C virus (HCV) infection. Hepatitis C is a liver infection caused by the hepatitis C virus. Veltasof works by directly targeting the virus to prevent it from replicating in the body, which can lead to a sustained virologic response (SVR) and a functional cure of the infection.

Veltasof tablets contain a combination of two direct-acting antiviral (DAA) agents:

• Sofosbuvir (400 mg): A nucleotide analog NS5B polymerase inhibitor.

• Velpatasvir (100 mg): A pan-genotypic NS5A inhibitor.

These two components work synergistically to block different stages of the HCV replication cycle, which makes the combination highly effective against multiple genotypes of the virus.

• Treatment of chronic hepatitis C: Veltasof is used to treat chronic hepatitis C virus infection in adults.

• It is effective for various HCV genotypes (including 1, 2, 3, 4, 5, and 6) and can be used in patients with or without cirrhosis.

• In some cases, it may be used in combination with other medications like ribavirin, especially for patients with a more advanced liver disease.

• The usual dose is one tablet once a day.

• Veltasof can be taken with or without food.

• The duration of treatment can vary, but it is typically 12 weeks. Your doctor will determine the appropriate duration and treatment regimen based on your specific condition, viral genotype, and previous treatment history.

While generally well-tolerated, some common side effects of Veltasof may include:

• Headache

• Fatigue

• Nausea

• Insomnia

• Diarrhea

• Hepatitis B: Before starting treatment, your doctor will likely screen you for hepatitis B virus (HBV) infection. In some cases, taking Veltasof can cause a reactivation of a pre-existing hepatitis B infection, which can be a serious medical concern.

• Drug Interactions: Veltasof can interact with other medications, including certain antacids, proton pump inhibitors, and some medications for heart conditions. It is crucial to inform your doctor about all the medications, vitamins, and herbal supplements you are taking.

• Heart Problems: Use with caution in patients with heart conditions, especially if taking amiodarone, due to the risk of severe bradycardia (slow heart rate).

• Pregnancy and Breastfeeding: The use of Veltasof in pregnant or breastfeeding women has not been extensively studied, and the risks and benefits should be discussed with a doctor.

Viraday is a fixed-dose combination of three antiviral medicines used for the treatment of Human Immunodeficiency Virus (HIV) infection. It is an antiretroviral medication that helps to manage the disease and improve the quality of life for individuals with HIV.

Viraday tablets contain a combination of three active ingredients:

• Efavirenz (600 mg): A non-nucleoside reverse transcriptase inhibitor (NNRTI).

• Emtricitabine (200 mg): A nucleoside reverse transcriptase inhibitor (NRTI).

• Tenofovir Disoproxil Fumarate (300 mg): A nucleotide reverse transcriptase inhibitor (NtRTI).

These medications work together to inhibit the reverse transcriptase enzyme, which is essential for HIV to multiply in the body. By preventing viral replication, Viraday helps to decrease the viral load and strengthen the immune system, thereby reducing the risk of HIV-related complications.

• Treatment of HIV-1 infection: Viraday is a primary medication in a regimen known as Antiretroviral Therapy (ART).

• It is not a cure for HIV or AIDS but is highly effective in controlling the virus.

• The typical dose for adults and children weighing at least 40 kg is one tablet once a day.

• It is usually recommended to take Viraday on an empty stomach, preferably at bedtime, to help reduce potential side effects like dizziness and drowsiness.

• It is crucial to follow the prescribed dosage and not skip doses to prevent the virus from developing resistance to the medication.

While Viraday can be highly effective, it may cause side effects, including:

• Dizziness, drowsiness, and headache

• Gastrointestinal issues like nausea, vomiting, and diarrhea

• Rash

• Abnormal dreams or trouble sleeping

• Fatigue

• Mental Health: Viraday may cause psychiatric side effects such as depression, anxiety, or suicidal thoughts. Individuals with a history of mental health issues should use this medication with caution.

• Kidney and Liver Health: This medication can affect kidney and liver function. Your doctor may monitor these functions regularly with blood tests.

• Bone Density: Long-term use of Tenofovir can lead to a decrease in bone mineral density.

• Pregnancy: Viraday may cause birth defects. Effective contraception should be used during treatment and for a period after stopping the medication.

• Drug Interactions: Viraday can interact with other medications, including certain antifungals and anticonvulsants. Always inform your doctor about all the medicines you are taking.

VIROPIL tablets are a fixed-dose combination of three antiretroviral drugs used in the treatment of Human Immunodeficiency Virus (HIV) infection. This medication is a part of highly active antiretroviral therapy (HAART), and it works by suppressing the replication of the HIV virus in the body.

Each VIROPIL tablet contains:

• Dolutegravir (50 mg): This is an integrase strand transfer inhibitor (INSTI). It works by blocking the HIV integrase enzyme, which the virus needs to integrate its genetic material into the DNA of the host cell. By inhibiting this process, it prevents the virus from multiplying.

• Lamivudine (300 mg): This is a nucleoside reverse transcriptase inhibitor (NRTI). It interferes with the reverse transcriptase enzyme, which is crucial for the virus to convert its RNA into DNA. This action effectively stops the virus from replicating.

• Tenofovir Disoproxil Fumarate (300 mg): This is another NRTI, a prodrug that is converted into the active drug tenofovir. Similar to lamivudine, it inhibits the reverse transcriptase enzyme, preventing viral replication.

• Treatment of HIV-1 Infection: VIROPIL is indicated for the management of HIV-1 infection in adults and adolescents (typically those weighing 35 kg or more).

• Reduces Viral Load and Boosts Immunity: The combination of these three drugs works to reduce the amount of HIV in the blood (viral load) and increase the count of CD4 cells, which are a key part of the immune system. This helps the body fight off other infections and illnesses.

• Post-Exposure Prophylaxis (PEP): In some cases, it may also be used as a part of a regimen for Post-Exposure Prophylaxis to reduce the risk of HIV infection after potential exposure.

Common side effects of VIROPIL are generally mild and may include:

• Headache

• Nausea and vomiting

• Diarrhea

• Fatigue or weakness

• Insomnia (difficulty sleeping)

• Dizziness

• Rash

More serious, but less common, side effects can occur, and patients should seek immediate medical attention if they experience symptoms like:

• Signs of a severe allergic reaction (fever, rash, swelling)

• Liver toxicity (yellowing of the skin or eyes, dark urine)

• Kidney problems

• Depression or other severe mood changes

• VIROPIL is a prescription-only medication and should only be taken under the guidance of a healthcare professional.

• Dosage adjustments may be necessary for patients with kidney or liver problems.

• It is crucial to take the medication exactly as prescribed and not to miss doses, as this can lead to the development of drug-resistant strains of HIV.

• VIROPIL is not a cure for HIV and does not prevent the transmission of the virus. Safe practices, such as using condoms, are still necessary to prevent transmission.